Understanding the Link Between Depression Medications and Dry Mouth

added on: December 24, 2024

The winter months can feel long and gloomy. For many, shorter days and colder temperatures can lead to a dip in mood, commonly known as Seasonal Affective Disorder (SAD). Depression and anxiety can impact overall health, and so can the medications used to treat them. One side effect many people don’t realize is how these medications can affect oral health, particularly by causing dry mouth.

What Is Dry Mouth?

Dry mouth, or xerostomia, happens when your mouth doesn’t produce enough saliva. Saliva isn’t just for helping you chew and swallow; it’s also crucial for:

  • Washing away food particles
  • Neutralizing acids in the mouth
  • Preventing cavities
  • Protecting gums from infection

Without enough saliva, your mouth can become uncomfortable, and your teeth and gums are more vulnerable to problems like tooth decay and gum disease.

Why Do Depression Medications Cause Dry Mouth?

Many medications used to treat depression, including those for Seasonal Affective Disorder (SAD), can cause dry mouth as a side effect. These medications often belong to categories such as:

  • Selective Serotonin Reuptake Inhibitors (SSRIs)

Examples include Zoloft, Prozac, and Lexapro.

  • Tricyclic Antidepressants (TCAs)

Examples include Elavil and Tofranil.

  • Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)

Examples include Effexor and Cymbalta.

These medications can affect how your body regulates saliva production, leading to a dry, sticky feeling in the mouth.

Signs You Might Have Dry Mouth

Whether or not you’re taking antidepressants, it’s important to be aware of the signs of dry mouth, which include:

  • A dry or sticky feeling in the mouth
  • Frequent thirst
  • Difficulty chewing, swallowing, or speaking
  • Cracked lips or sores in the corners of the mouth
  • A burning sensation on the tongue
  • Bad breath

Left untreated, dry mouth can lead to more serious oral health issues.

5 Ways to Manage Dry Mouth

Fortunately, there are ways to reduce dry mouth and protect your oral health. Here are some tips:

  1. Stay Hydrated
  • Drink plenty of water throughout the day.
  • Avoid caffeine and alcohol, which can make dry mouth worse.
  1. Use a Humidifier
  • Adding moisture to the air can help keep your mouth and throat from drying out, especially during the winter.
  1. Chew Sugar-Free Gum
  • Chewing gum or sucking on sugar-free candies can help stimulate saliva production. Look for products with xylitol, which also helps prevent cavities.
  1. Maintain Good Oral Hygiene
  • Brush your teeth twice a day with a fluoride toothpaste.
  • Floss daily to remove food particles and plaque.
  • Consider using an alcohol-free mouthwash designed for dry mouth.
  1. Talk to Your Dentist
  • Regular dental check-ups are essential. Your dentist in Broomfield can spot early signs of tooth decay or gum disease and recommend specific treatments or products to help manage dry mouth just as a prescription mouthwash or saliva substitute.

If dry mouth is severe, ask your healthcare provider if adjusting your medication or dosage might help. Never stop taking medications without talking to your doctor first. 

Dry mouth may seem like a minor inconvenience, but it can lead to serious dental problems if left untreated. Taking small steps to manage dry mouth can help keep your smile healthy and your overall health in check.

If you’re experiencing dry mouth, don’t hesitate to schedule an appointment at our Broomfield dental office. We’re here to support your oral health through regular check-ups, personalized advice, and proactive care every season to help ensure that your smile stays bright and healthy – no matter how dark the winter days get.

About The Author
Dr. Samuel J. Sweeny

Dr. Samuel J. Sweeny used to spend his summers working in his dad's dental clinic, where he was first exposed to endodontics (root canal), pediatrics, and orthodontics. This experience sparked his passion for dentistry. Inspired by Frank Spear, founder/director of SPEAR Education, he committed to pursuing dental excellence by taking continuing education courses at SPEAR and serving as a mentor and visiting faculty member. Dr. Sweeny is a Fellow at the Academy of General Dentistry and is affiliated with several associations.


The winter months can feel long and gloomy. For many, shorter days and colder temperatures can lead to a dip in mood, commonly known as Seasonal Affective Disorder (SAD). Depression and anxiety can impact overall health, and so can the medications used to treat them. One side effect many people… Read More…